We are passionate about providing safe, evidence-based solutions for sustainable weight loss. Medical weight management has evolved far beyond diet and exercise alone. Today, we offer a range of FDA-approved medications and medical-grade supplements that target the biological drivers of weight gain, making your journey more effective and personalized. In this guide, we break down the science, uses, and benefits of GLP-1 agonists, Contrave, Phentermine, Naltrexone, and supportive supplements.

Understanding Medical Weight Loss

Medical weight loss combines clinical expertise with advanced therapies to help you achieve and maintain a healthy weight. Unlike fad diets, our approach is grounded in science and tailored to your unique biology, lifestyle, and goals. Our Omaha-based team provides comprehensive assessments, ongoing monitoring, and personalized plans for optimal results.

Comprehensive Evaluation: We assess metabolic rate, hormone balance, medical history, and lifestyle factors to design a custom plan.

Ongoing Support: Our team offers regular check-ins, education, and motivation to help you stay on track.

Long-Term Success: The goal is not just weight loss, but sustainable health and confidence.

GLP-1 Agonists: Modern Science for Lasting Results

GLP-1 (glucagon-like peptide-1) agonists are a breakthrough class of medications originally developed for diabetes management. They work by mimicking a natural hormone that regulates appetite, slows stomach emptying, and helps control blood sugar. Popular GLP-1 agonists include semaglutide (Wegovy, Ozempic) and liraglutide (Saxenda, Victoza).

1. Promote a feeling of fullness, reducing overeating and snacking

2. Support steady, clinically significant weight loss

3. May improve cardiovascular and metabolic health, lowering risks of diabetes and heart disease

4. Can help break through weight loss plateaus that often occur with diet and exercise alone

Recent clinical trials have shown that GLP-1 agonists can help patients lose 10-15% of their body weight on average, especially when combined with lifestyle changes. These medications are typically administered as a once-weekly injection, and most patients tolerate them well with minimal side effects such as mild nausea or digestive changes that usually resolve over time.

Contrave: Dual-Action Appetite Control

Contrave is an FDA-approved combination of bupropion and naltrexone. It targets two key areas in the brain that regulate hunger and cravings. Bupropion is an antidepressant that can reduce appetite and boost energy, while naltrexone blocks reward signals associated with eating. Together, they help curb emotional eating and addictive food behaviors.

1. Reduces cravings for unhealthy foods, especially in the evening or during stressful times

2. Helps control emotional and binge eating, supporting a healthier relationship with food

3. Can be used alongside behavioral therapy or counseling for best results

4. May support weight maintenance after initial weight loss

Contrave is generally taken as a daily oral tablet, with dosage gradually increased to minimize side effects such as headache or mild nausea. It has been shown to help patients lose up to 5-10% of their body weight in clinical studies.

Phentermine: Jump-Starting Your Journey

Phentermine is a prescription appetite suppressant that has been safely used for decades as a short-term kickstart for weight loss. It works by stimulating the release of neurotransmitters that decrease hunger and increase energy. Phentermine is most effective when combined with lifestyle counseling and is typically used for a few weeks to months under close medical supervision.

1. Reduces appetite and boosts energy, making it easier to stick to a calorie deficit

2. Helps break through weight loss plateaus or initiate rapid weight loss when needed

3. Ideal for patients needing a motivational boost at the start of their journey

4. Not recommended for long-term use due to potential for tolerance and side effects (such as dry mouth, insomnia, or increased heart rate)

Phentermine is usually prescribed as a daily tablet or capsule, and patients are closely monitored for blood pressure, heart rate, and overall well-being throughout therapy.

Naltrexone: Supporting Self-Control and Long-Term Change

Naltrexone is best known for its use in addiction medicine but is increasingly recognized as a valuable tool in weight management. It helps modulate the brain’s reward system, reducing the urge for compulsive eating and supporting long-term behavior change. Naltrexone is often used in combination therapies like Contrave or alongside other weight loss medications.

1. Decreases food-related reward sensations, making it easier to resist cravings

2. Supports long-term lifestyle and behavior change, not just short-term weight loss

3. Can be tailored to individual needs and combined with other therapies for enhanced effect

4. May be used in patients with a history of emotional or binge eating

Naltrexone is generally well tolerated, with the most common side effects being mild digestive upset or headache. It is available as a standalone medication or as part of combination therapies.

Medical-Grade Supplements: Optimizing Metabolism and Wellness

In addition to prescription medications, we recommend supportive supplements that address nutritional gaps and metabolic health. Medical-grade supplements are formulated for purity and potency, often including ingredients such as:

1. High-quality protein to preserve muscle mass during weight loss

2. Essential vitamins and minerals (like vitamin D, magnesium, B12) to support energy and metabolism

3. Probiotics for gut health and appetite regulation, as a healthy microbiome influences weight

4. Omega-3 fatty acids for inflammation and metabolic support

5. Adaptogens and botanicals for energy, stress resilience, and hormonal balance

Our team will recommend supplements based on your lab results and unique needs, ensuring a holistic, evidence-based approach. Supplements can help prevent nutrient deficiencies, support fat loss, and enhance overall well-being during your weight loss journey.

Why Choose Us?

Our clinic blends advanced science, compassionate care, and ongoing support. We use only FDA-approved medications and premium supplements, tailoring every plan to your goals and medical history. Our team is dedicated to your long-term success, offering education, accountability, and encouragement every step of the way. We believe in treating the whole person, not just the number on the scale.

Get Started Today

If you’re ready to take control of your health and achieve lasting weight loss, contact our us for a personalized consultation. Together, we’ll create a plan that works for you—backed by science, guided by care. Every journey is unique, and we are here to support you at every stage.

Disclaimer: All medications and supplements should be used under medical supervision. Individual results may vary. These treatments are not intended to diagnose, treat, cure, or prevent any disease.

References

1. NEJM, 2021 – Semaglutide in adults with obesity

2. Obesity (Silver Spring), 2016 – Contrave efficacy and safety

3. JAMA, 2019 – Phentermine/topiramate for weight loss

4. Frontiers in Endocrinology, 2022 – Naltrexone in metabolic regulation

5. Nutrition Reviews, 2020 – Role of supplements in weight management